Upper threshold of extracellular neural stimulation

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Upper Threshold of Extracellular Neural Stimulation 1 Running Head : Upper Threshold of Extracellular Neural Stimulation

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Upper threshold of extracellular neural stimulation.

It is well known that spiking neurons can produce action potentials in response to extracellular stimulation above certain threshold. It is widely assumed that there is no upper limit to somatic stimulation, except for cellular or electrode damage. Here we demonstrate that there is an upper stimulation threshold, above which no action potential can be elicited, and it is below the threshold of ...

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On the upper threshold phenomenon of extracellular neural stimulation.

TO THE EDITOR: Although the authors reported interesting findings (Boinagrov et al. 2012), well-known facts such as “the axon is the most excitable part of a neuron” (Nowak and Bullier 1998) or “axonal sodium-channel bands shape the response to electric stimulation in retinal ganglion cells” (Fried et al. 2009) cannot be shown using their presented simple spherical neuron model. Therefore, I re...

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Exploring Selective Neural Electrical Stimulation for Upper Limb Function Restoration

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Asymmetric Rectangular Waveform in Stimulation with High Frequency Alternating Current Reduces the Threshold for Neural Conduction Block

Introduction Abnormal neural impulses in the nervous system may lead to various diseases and disabilities. High frequency alternating currents (HFAC) has been used to block the propagation of such impulses and improve the symptoms or disabilities. The technique is safe, reversible, and relatively selective, and its reliability, the optimum stimulation parameters, and elimination of the onset re...

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ژورنال

عنوان ژورنال: Journal of Neurophysiology

سال: 2012

ISSN: 0022-3077,1522-1598

DOI: 10.1152/jn.01058.2011